منابع مشابه
A single mutation inside the NPA motif of aquaporin-1 found in a Colton-null phenotype.
2, as well as intron 1 and part of intron 2 was amplified by polymerase chain reaction (PCR). Amplification primers were based on the L-ferritin sequence published by Santoro et al4 (GenBank accession no. X03742). DNA fragments were subsequently cloned and more than 10 clones from each patient were sequenced by automated DNA sequencing. Sequence analysis identified a point mutation, C to T, at ...
متن کاملA Single Mutation Inside the NPA Motif of Aquaporin - 1 Found in a Colton - Null Phenotype
2, as well as intron 1 and part of intron 2 was amplified by polymerase chain reaction (PCR). Amplification primers were based on the L-ferritin sequence published by Santoro et al4 (GenBank accession no. X03742). DNA fragments were subsequently cloned and more than 10 clones from each patient were sequenced by automated DNA sequencing. Sequence analysis identified a point mutation, C to T, at ...
متن کاملAn AQP1 allele associated with co(a-b-) phenotype.
The Colton (CO) blood group system consists of four antigens, Co(a), Co(b), Co3, and Co4, located on aquaporin-1 (AQP1), with Co(a) highly prevalent in all populations (99.8%). The Colton null phenotype, Co(a-b-), is very rare, and individuals with this phenotype lack the high-prevalence antigen Co3. To date, only six Co(a-b-) probands have been reported and four silencing alleles characterized...
متن کاملAssociation of ABO and Colton Blood Group Gene Polymorphisms With Hematological Traits Variation
Hematological parameters are appraised routinely to determine overall human health and to diagnose and monitor certain diseases. In GWASs, more than 30 loci carrying common deoxyribonucleic acid (DNA) polymorphisms have been identified related to hematological traits. In this study, we investigated the contribution of ABO rs2073823 along with AQP1 rs1049305 and rs10244884 polymorphisms in hemat...
متن کاملEffects of Acetazolamide Combined with or without NaHCO3 on Suppressing Neoplasm Growth, Metastasis and Aquaporin-1 (AQP1) Protein Expression
This study was made to explore the effects of acetazolamide on tumor growth, metastasis and the possible mechanisms. The mice bearing with Lewis lung carcinomas were taken as the animal model. The effects of acetazolamide were compared with the combination treatment of NaHCO3 on tumor growth, metastasis and carbonic anhydrase activity in lung and tumor tissues using imidazole-Tris technique. An...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2019
ISSN: 1768-3262
DOI: 10.4267/2042/70645